Sleep correlates of cognition in early course psychotic disorders

Sleep spindle deficits in antipsychotic-naïve early course schizophrenia and in non-psychotic first-degree relatives

INTRODUCTION Chronic medicated patients with schizophrenia have marked reductions in sleep spindle activity and a correlated deficit in sleep-dependent memory consolidation. Using archival data, we investigated whether antipsychotic-naïve early course patients with schizophrenia and young non-psychotic first-degree relatives of patients with schizophrenia also show reduced sleep spindle activit...

Oxytocin and social cognition in affective and psychotic disorders.

Impairments in social cognition are now recognized as core illness features in psychotic and affective disorders. Despite the significant disability caused by social cognitive abnormalities, treatments for this symptom dimension are lacking. Here, we describe the evidence demonstrating abnormalities in social cognition in schizophrenia, major depressive disorder, and bipolar disorder, as well a...

Suicidality in psychotic disorders; demographical, clinical, and neurocognitive correlates

The sleep quality and prevalence of sleep disorders in adolescents

Sleep has a key role in the development of adolescents. Sleep is effective not only in physical growth, but also in behavior, emotion, cognition, attention, and school performance of adolescents. The purpose of the present study was to investigate the quality of sleep and the prevalence of sleep disorders in adolescents of Gonabad city. The statistical sample consisted of 1153 adolescents study...

Acute and transient psychotic disorders: precursors, epidemiology, course and outcome.

BACKGROUND ICD-10 has introduced the diagnostic group acute and transient psychotic disorders (ATPDs; F23). AIMS To validate the nosological distinctiveness of ICD-10 ATPDs by following up an inception cohort with first-episode psychosis. METHOD All patients with first-episode psychosis identified in Nottingham between 1992 and 1994 and diagnosed using ICD-10 criteria were reassessed 3 year...